Johannes G van der Hoeven Selected Research

Escherichia coli endotoxin

5/2014	Voluntary activation of the sympathetic nervous system and attenuation of the innate immune response in humans.
1/2014	Body mass index is not associated with cytokine induction during experimental human endotoxemia.
2/2009	Inflammation-induced hepatotoxicity in humans.

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Johannes G van der Hoeven Research Topics

Disease

28	Inflammation (Inflammations) 01/2020 - 12/2004
28	Endotoxemia 01/2020 - 01/2005
23	Sepsis (Septicemia) 01/2021 - 04/2005
22	Critical Illness (Critically Ill) 10/2021 - 02/2006
18	Septic Shock (Toxic Shock Syndrome) 01/2020 - 12/2003
13	Delirium 01/2021 - 01/2010
9	Heart Arrest (Cardiac Arrest) 01/2017 - 12/2004
8	Coma (Comas) 01/2021 - 07/2010
6	Hypoxia (Hypoxemia) 01/2019 - 01/2010
5	Chronic Obstructive Pulmonary Disease (COPD) 09/2020 - 01/2012
4	Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome) 01/2022 - 07/2015
4	Infections 01/2018 - 03/2010
4	Hypothermia 10/2014 - 07/2010
4	Body Weight (Weight, Body) 01/2012 - 02/2009
3	COVID-19 01/2021 - 12/2020
3	Wounds and Injuries (Trauma) 06/2020 - 11/2010
3	Muscular Atrophy (Muscle Atrophy) 03/2015 - 01/2011
3	Atrophy 02/2014 - 01/2011
3	Bacterial Infections (Bacterial Infection) 06/2010 - 02/2008
3	Lung Injury 03/2010 - 10/2009
3	Ventilator-Induced Lung Injury 10/2009 - 01/2008
2	Hyperventilation 12/2021 - 05/2014
2	Acute Kidney Injury (Acute Renal Failure) 01/2021 - 01/2012
2	Pneumothorax 06/2020 - 05/2004
2	Brain Injuries (Brain Injury) 11/2019 - 10/2014
2	Respiratory Insufficiency (Respiratory Failure) 01/2019 - 12/2013
2	Pain (Aches) 09/2018 - 01/2013
2	Shock 01/2018 - 06/2010
2	Neoplasms (Cancer) 01/2017 - 08/2013
2	Heart Failure 04/2016 - 01/2012
2	Hyperoxia 11/2015 - 01/2011
2	Anemia 10/2014 - 01/2011
2	Ventricular Fibrillation 10/2014 - 08/2012
2	Pulmonary Edema 06/2014 - 09/2011
2	Acidosis 06/2012 - 03/2008
2	Sudden Infant Death (SID) 06/2012 - 02/2006
2	Out-of-Hospital Cardiac Arrest 01/2011 - 07/2010
1	Frailty 02/2022
1	Fatigue 02/2022
1	Post-Traumatic Stress Disorders (Post Traumatic Stress Disorder) 02/2022
1	Neurobehavioral Manifestations 02/2022
1	Postoperative Cognitive Complications 11/2021

Drug/Important Bio-Agent (IBA)

22	CytokinesIBA 01/2020 - 01/2005
10	EndotoxinsIBA 07/2018 - 12/2004
9	Norepinephrine (Noradrenaline)FDA LinkGeneric 01/2022 - 12/2003
9	LipopolysaccharidesIBA 12/2019 - 06/2007
9	Interleukin-6 (Interleukin 6)IBA 01/2018 - 04/2006
8	Interleukin-10 (Interleukin 10)IBA 07/2018 - 04/2006
8	Adenosine (Adenocard)FDA LinkGeneric 07/2018 - 07/2006
7	Oxygen (Dioxygen)IBA 01/2016 - 09/2009
5	Haloperidol (Haldol)FDA LinkGeneric 01/2021 - 01/2013
5	InterleukinsIBA 07/2018 - 04/2006
4	AcidsIBA 12/2021 - 02/2006
4	Interleukin 1 Receptor Antagonist Protein (Anakinra)FDA Link 12/2020 - 01/2011
4	Proteins (Proteins, Gene)FDA Link 01/2018 - 09/2009
4	Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA 03/2015 - 07/2006
4	Nitric Oxide Synthase (NO Synthase)IBA 06/2010 - 07/2004
3	Hypnotics and Sedatives (Sedatives)IBA 01/2021 - 02/2014
3	Vasopressins (Vasopressin)IBA 01/2020 - 12/2003
3	HepcidinsIBA 01/2019 - 01/2011
3	Biomarkers (Surrogate Marker)IBA 01/2018 - 01/2011
3	ChemokinesIBA 03/2015 - 04/2012
3	Escherichia coli endotoxinIBA 05/2014 - 02/2009
3	Hydrocortisone (Cortisol)FDA LinkGeneric 06/2012 - 01/2010
3	Interleukin-8 (Interleukin 8)IBA 04/2012 - 04/2006
2	Adrenal Cortex Hormones (Corticosteroids)IBA 12/2020 - 01/2020
2	Vasoconstrictor AgentsIBA 01/2020 - 08/2006
2	esmolol (Brevibloc)FDA LinkGeneric 12/2019 - 01/2018
2	Amyloid (Amyloid Fibrils)IBA 01/2018 - 01/2011
2	GlucocorticoidsIBA 01/2015 - 09/2009
2	EnzymesIBA 01/2015 - 02/2009
2	IronIBA 10/2014 - 03/2014
2	ChloridesIBA 06/2012 - 02/2006
2	CatecholaminesIBA 06/2012 - 12/2003
2	Cell Adhesion MoleculesIBA 04/2012 - 01/2011
2	Alkaline PhosphataseIBA 01/2012 - 02/2009
2	C-Reactive ProteinIBA 03/2011 - 06/2007
2	NucleosidesIBA 01/2011 - 01/2011
2	ProcalcitoninIBA 01/2011 - 09/2009
2	Carbon DioxideIBA 07/2010 - 01/2010
2	Methylene Blue (Methylthioninium Chloride)FDA Link 06/2010 - 02/2008
2	Nitric Oxide (Nitrogen Monoxide)FDA Link 09/2009 - 08/2006
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 02/2009 - 04/2006
2	AnionsIBA 03/2008 - 01/2008
1	4-amino-4'-hydroxylaminodiphenylsulfone (HADS)IBA 02/2022

Therapy/Procedure

18	Artificial Respiration (Mechanical Ventilation) 01/2021 - 09/2008
10	Mechanical Ventilators (Ventilator) 10/2021 - 03/2010
8	Induced Hypothermia 01/2017 - 01/2011
6	Therapeutics 01/2020 - 03/2010
6	Resuscitation 12/2019 - 06/2010
5	Length of Stay 01/2021 - 07/2012
5	Critical Care (Surgical Intensive Care) 01/2019 - 01/2010
4	Noninvasive Ventilation 09/2020 - 12/2013
2	Cardiopulmonary Resuscitation (CPR) 06/2020 - 12/2012
2	Hydrotherapy (Whirlpool Bath) 12/2018 - 02/2015
2	Vagus Nerve Stimulation 06/2015 - 01/2012
2	Rewarming 10/2014 - 04/2012
2	Meditation 05/2014 - 06/2012
2	Intravenous Administration 01/2014 - 06/2012
1	Coronary Artery Bypass (Coronary Artery Bypass Surgery) 11/2021